- New generation cell therapy to cure type 1 Diabetes
The VANGUARD project aims to generate a bioartificial vascularized and immunoprotected pancreas that can be transplanted into non-immunosuppressed patients, combining advanced elements of tissue engineering such as 3D organoids, hydrogel design, the assembly of bioartificial organs and gene editing via CRISPR-Cas9.
This approach will produce cell therapy in the form of an advanced therapy medicinal product (ATMP), which can significantly improve the treatment of type 1 diabetes.
The project involves a consortium with 9 partners from 5 European countries.
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