- Role of the ICOS/ICOSL system in Frailty Syndrome

https://www.uniupo.it/en/research/research-projects/role-icosicosl-system-frailty-syndrome

Funding

Funding body
Fondazione Cariplo
Call
Ricerca malattie e invecchiamento- 2017
Budget
280.000,00 €

Departments and Centres

Departments

DISS

Department of Health Sciences

Centri interdipartimentali coinvolti
CAAD - Centro Interdipartimentale "Centro di Eccellenza per la Ricerca traslazionale sulle Malattie Autoimmuni ed Allergiche"

Staff

Principle Investigator
Umberto DIANZANI
Working group

Umberto Dianzani
Emanuele Albano
Flavia Prodam
Annalisa Chiocchetti

Project duration

Start date
End date

Project in collaboration with the University of Turin (Prof.P.D'Amelio is Head of the UNITO department).

The project looks at the role of the ICOS/ICOSL system in bone and metabolic fragility in elderly people with Fragility Syndrome. The ICOS/ICOSL system was studied at length in the past regarding immune response, but more recent data collected by the project members demonstrates that it is also involved in bone metabolism.