Since 2004, when UPO issued regulations on the establishment of spin-off companies, 25 advanced tech companies have been set up by the Università del Piemonte Orientale (and, since 2009 by the Enne3 Business Incubator) as part of the Spin-off brand.

The current Spin-off Committee was appointed by the Rector’s Decree of 06/11/2018 and is composed of: