In Alessandria there are two university hubs:
- Palazzo Borsalino, located at the crossroads between via Cavour and corso Cento Cannoni, once home to the renowned hatter’s business. This is home to the Department of Law, and Political, Economic and Social Sciences (DiGSPES)
- Palazzo del DISIT, a new building in viale Teresa Michel, in the Orti district, which once housed the Forum Boarium (cattle market). This is home to the Department of Science, Technology and Innovation
Administrative offices and teachers’ offices of DiGSPES are also located in the former centre Agorà di Largo Ambrosoli and in Via Mondovì 6/10.